New tool of interest: GraftM: “a tool for scalable, phylogenetically informed classification of genes within metagenomes”

This could be of use to many people: Source: GraftM: a tool for scalable, phylogenetically informed classification of genes within metagenomes | Nucleic Acids Research | Oxford Academic Large-scale metagenomic datasets enable the recovery of hundreds of population genomes from environmental samples. However, these genomes do not typically represent the full diversity of complex microbial …

An informative glimpse into the drug factory microbiome: Which bugs coexist with our drugs? The story behind the paper

The story behind: Toward the Drug Factory Microbiome: Microbial Community Variations in Antibiotic-Producing Clean Rooms (OMICS. 2018 Feb;22(2):133-144. doi: 10.1089/omi.2017.0091.) PMID: 28873001 [Preprint] It was in 2013, on my return to Cairo University after a couple of years as a visiting scientist at UCSD, that I met Amal for the first time. Amal was a fresh master’s …

Another RDP for microbiologists to check out ..

Just came across this paper on bioRXiv. A Measure of Open Data: A Metric and Analysis of Reusable Data Practices in Biomedical Data Resources by Seth Carbon, Robin Champieux, Julie McMurry, Lilly Winfree, Letisha R Wyatt, and Melissa Haendel Abstract Data is the foundation of science, and there is an increasing focus on how data can be reused …

Paper of possible interest: KatharoSeq Enables High-Throughput Microbiome Analysis from Low-Biomass Samples

This may be of interest to people out there.  Source: KatharoSeq Enables High-Throughput Microbiome Analysis from Low-Biomass Samples | mSystems Abstract: Microbiome analyses of low-biomass samples are challenging because of contamination and inefficiencies, leading many investigators to employ low-throughput methods with minimal controls. We developed a new automated protocol, KatharoSeq (from the Greek katharos [clean]), …

Postdoc Opportunity for Computational Microbial Ecologist in Seattle

  The Gibbons group at the Institute for Systems Biology (ISB) is seeking a computationally-oriented Postdoctoral Fellow with interests in microbial ecology, evolution, and human health. The successful applicant will work with an interdisciplinary team of microbiologists, systems biologists, bioinformaticians, and clinical researchers to:  Integrate and analyze multi-omic data from Arivale as part of the …

So you want to run FACS on your microbiome samples…

So you want to run FACS on your microbiome samples… By Cara Pardon Although optimized for eukaryotic cell research, an increasingly common technique used in the microbiome field is Fluorescence Activated Cell Sorting (FACS).  From sorting cells for single cell genomics to identifying the host range of a plasmid; from detecting metabolically active cells in …