Evolution happens: Bacteria becoming resistant to hospital disinfectants

Well, if true this is both troubling and not surprising: Bacteria becoming resistant to hospital disinfectants, warn scientists | Society | The Guardian The story reports on a paper in Science Translational Medicine. Some quotes: The results reveal that Enterococcus faecium bacteria have become more tolerant to alcohol over that time. “We found that the new …

A new, and scary, fungus among us #MoBE #Candida

Fascinating, scary and really important read from Maryn McKenna in Wired: The Strange and Curious Case of the Deadly Superbug Yeast By the normal standards of outbreak, Candida auris signals a mind-bending shift—and it’s forcing researchers draw on some of medicine’s oldest practices to rethink treatment.   The article tells the tale of Candida auris a fungus that …

Paper of interest: Predicting antibiotic resistance from full genome sequences 

This preprint seems like it may be of interest to folks: Precise prediction of antibiotic resistance in Escherichia coli from full genome sequences | bioRxiv Basically, the authors showed that, using a machine learning approach, they can quite accurately predict antibiotic resistance in E. coli from whole genome data. The emergence of microbial antibiotic resistance …

An informative glimpse into the drug factory microbiome: Which bugs coexist with our drugs? The story behind the paper

The story behind: Toward the Drug Factory Microbiome: Microbial Community Variations in Antibiotic-Producing Clean Rooms (OMICS. 2018 Feb;22(2):133-144. doi: 10.1089/omi.2017.0091.) PMID: 28873001 [Preprint] It was in 2013, on my return to Cairo University after a couple of years as a visiting scientist at UCSD, that I met Amal for the first time. Amal was a fresh master’s …

New paper of interest on Hospital Plumbing and Carbapenem Resistance

New paper of interest:: Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance Weingarten RA, Johnson RC, Conlan S, Ramsburg AM, Dekker JP, Lau AF, Khil P, Odom RT, Deming C, Park M, Thomas PJ, NISC Comparative Sequencing Program, Henderson DK, Palmore TN, Segre JA, Frank KM. 2018. Genomic analysis …

Paper of interest: antibiotic resistance and the safety of reusing treated wastewater

Paper of possible interest: Hong, P.-Y.; Julian, T.R.; Pype, M.-L.; Jiang, S.C.; Nelson, K.L.; Graham, D.; Pruden, A.; Manaia, C.M. Reusing Treated Wastewater: Consideration of the Safety Aspects Associated with Antibiotic-Resistant Bacteria and Antibiotic Resistance Genes. Water 2018, 10, 244. Abstract: As more countries engage in water reuse, either intended or de facto, there is …

Of potential interest: factors influencing antimicrobial use in global aquaculture #

This may be of interest to folks. Multiple stakeholders have, as a result, criticized the aquaculture industry, resulting in consequent regulations in some countries. AM use in aquaculture differs from that in livestock farming due to aquaculture’s greater diversity of species and farming systems, alternative means of AM application, and less consolidated farming practices in …

New paper of interest: Unpacking factors influencing antimicrobial use in global aquaculture

This paper may be of interest: Unpacking factors influencing antimicrobial use in global aquaculture.    Henriksson, P.J.G., Rico, A., Troell, M. et al. Sustain Sci (2017). https://doi.org/10.1007/s11625-017-0511-8 Abstract: Global seafood provides almost 20% of all animal protein in diets, and aquaculture is, despite weakening trends, the fastest growing food sector worldwide. Recent increases in production have …

Antibiotics Use In Livestock: A Taste of Our Own Medicine 

There is a nice article by Katherine Wu on the history of antibiotic usage in livestock that is worth a look:  A Taste of Our Own Medicine – I Contain Multitudes – Medium This is part of the HHMI/Tangled Bank Studio’s series on “I Contain Multitudes” based on Ed Yong’s book of the same name. It …