Have you ever wondered what’s in the air of a daycare center, where kids swap microbes every day? A team from Virginia Tech and the University of Pittsburgh is investigating the viral ecology in air of a daycare center using metagenomics. We have collected samples on HVAC filters and are looking for a sequencing core with HiSeq capabilities, that has experience handling environmental samples with low DNA/RNA concentrations in which targeted sequencing is not possible. The sample extracts are ~50 microliters (ul) in volume with a concentration of ~0.1 nanograms per microliter (ng/ul). If you have any suggestions, please leave a comment.